Contents in brief: This study integrated multimodal profiling—including protein expression, single-cell RNA and ATAC sequencing, immunofluorescence, and spatial transcriptomics—to identify shared oncogenic features of high-risk DLBCL tumors and establish a proteomic framework for diagnosis and therapeutic decision-making.
Congrats to the co-authors of the A02 project, Julius Enßle, Björn Häupl and Thomas Oellerich, on this excellent work, exemplifying the breadth of our CRC's research.
Read the full article:
Enssle JC, Häupl B, ..., Oellerich T. Pathogenesis of diffuse large B cell lymphoma proteogenotypes. Cancer Cell. 2026 Jun 4:S1535-6108(26)00253-9. doi: 10.1016/j.ccell.2026.05.008. Epub ahead of print.
