Service project: Multiparametric analysis of lymphoma cells and their microenvironment

The overall aim of the CRC is to achieve progress in lymphoma therapy. Therefore, the members of the CRC aim to investigate key cellular mechanisms involved in B cell lymphomagenesis and therapy resistance, since these processes are complex. In order to support these aims, a central platform will be established for the multiparametric analysis of human and murine samples. It will provide cytometric, immunohistochemical, (epi-)genomic and proteomic analytics to all participants of the CRC to dissect the diversity of the malignant and non-malignant counterparts in lymphoid malignancies at bulk and single cell level by applying standardized protocols for the reproducible and reliable assessment and phenotyping of lymphoma. A close cooperation with the platform Z03 will allow to share, visualize, and inter-relate data.