Research Area A
Mechanisms of B cell-specific signaling pathways in lymphomagenesis
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A01
Using autochthonous mouse models of aggressive lymphoma to systematically distill actionable vulnerabilities
Prof. Dr. med. Hans Christian Reinhardt -
A02
The functional role of cytoskeletal dysregulation in activated B cell-like diffuse large B cell lymphoma
Prof. Dr. med. Thomas Oellerich -
A03
LUBAC und seine enzymatischen Aktivitäten bei der Entwicklung und Therapie des ABC-diffusen großzelligen B-Zell-Lymphoms
Prof. Dr. rer. nat. Henning Walczak, Dr. rer. nat. Gianmaria Liccardi -
A04
Role of apoptotic caspases in lymphomagenesis
Prof. Dr. rer. nat. Hamid Kashkar -
A05
Understanding the role of cFLIP in B cell lymphoma pathogenesis
Dr. rer. nat. Alessandro Annibaldi -
A06
Understanding resistance towards venetoclax in lymphoma: physiology of genetic alterations in BTG1 and BCL2
Prof. Dr. rer. nat. Ana García-Sáez, Dr. med. Lukas Frenzel
Research Area B
Understanding the molecular dialogues, cellular composition and plasticity of the lymphoma microenvironment
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B01
LYN kinase as a key regulator in the microenvironmental niche of B cell lymphoid tumors
Prof. Dr. med. Michael Hallek, Dr. rer. nat. Phuong-Hien Nguyen -
B02
Deciphering the role of BIRC3 in lymphomagenesis and resistance to therapy
Dr. rer. nat. Nieves Peltzer, Prof. Dr. med. Christian Pallasch -
B03
The role of ferroptosis in diffuse large B-cell lymphoma subtypes
Prof. Dr. rer. nat. Silvia von Karstedt -
B04
T cell-based mechanisms of immune evasion in aggressive B cell lymphomas
Prof. Dr. med. Dr. rer. nat. Sandrine Sander -
B05
New strategies to improve the efficiency and safety of CAR-T cells for the treatment of B cell lymphoma
Dr. rer. nat. Markus Chmielewski, Prof. Dr. med. Dr. nat. med. Roland Ullrich
Research Area C
Understanding the profound genetic and phenotypic heterogeneity of lymphoma
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C01
Tumor heterogeneity and genomic instability in classical Hodgkin lymphoma
Prof. Dr. rer. nat. Ralf Küppers -
C02
Harnessing defective DNA repair for the treatment of mantle cell lymphoma
Dr. med. Ron Jachimowicz -
C03
Proteogenomic characterization of mantle cell lymphoma
Prof. Dr. med. Reinhard Büttner, Prof. Dr. med. Thomas Oellerich -
C04
Modeling the clonal evolution of high-risk CLL
Prof. Dr. rer. nat. Martin Peifer, Dr. med. Kirsten Fischer -
C05
Characterization of Richter-transformed lymphoma and genomic instability as a potential vulnerability in 17p-deleted lymphomas
Prof. Dr. med. Björn Chapuy, Prof. Dr. med. Barbara Eichhorst
Z Projects
Central administrative project and program-specific projects: Integration and application of novel technologies and data management
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Z01
Central administration project
Prof. Dr. med. Michael Hallek -
Z02
Service project: Multiparametric analysis of lymphoma cells and their microenvironment
Prof. Dr. med. Reinhard Büttner, Prof. Dr. med. Thomas Oellerich, Dr. rer. nat. Nieves Peltzer, Dr. med. Lukas Frenzel, Prof. Dr. med. Dr. rer. nat. Michal Schweiger -
Z03
Information infrastructure project (INF): Bioinformatics and Data management
Prof. Dr. rer. nat. Martin Peifer, Dr. rer. nat. Nima Abedpour, Dr. rer. nat. Monica Valencia-Schneider